Table 1.
Participant demographics
| Subjectively sleepy controls, N = 48 | NT1, N = 46 | NT2, N = 12 | IH, N = 18 | |
|---|---|---|---|---|
| Mean age, years | 13.4 (3.6) | 12.9 (3.7) | 14 (2.9) | 16 (2) |
| Number of females (% female) | 22 (45.8) | 21 (45.7) | 5 (41.7) | 16 (88.9) |
| Number of Caucasian (% Caucasian) | 33 (68.8) | 25 (54.4) | 9 (75) | 12 (66.7) |
| BMI | 21.1 (4.5) | 26.3 (6.3) | 22.7 (4.1) | 23.9 (4.6) |
| HLA DQB1*06:02 (% positive) | 9 (18.8) | 41 (81.9) | 6 (50) | 4 (22.2) |
| Symptom duration, years | 3.5 (4.5) | 2.7 (2.5) | 5.3 (5.6) | 4.1 (3.8) |
| Drug naïve (% yes) | 27 (56.3) | 40 (87) | 7 (58.3) | 12 (66.7) |
| Epworth Sleepiness Score | 13.9 (3.7) | 17.5 (2.8) | 16.3 (3.2) | 13.18 (5.1) |
| MSLT mean sleep latency, minutes | 16.4 (2.8) | 3.3 (3) | 4.8 (2.5) | 8.8 (4.1)* |
| MSLT #SOREMPs | 0.2 (0.4) | 3.5 (1.4) | 2.7 (1.2) | 0.3 (0.5) |
Subjectively sleepy controls refer to subjectively sleepy patients who presented with self-reported daytime sleepiness but had normal sleep study testing. NT1, narcolepsy type 1; NT2, narcolepsy type 2; IH, idiopathic hypersomnia; MSLT, multiple sleep latency test. #SOREMPs = number of daytime sleep-onset REM periods. Values in parentheses are standard deviation unless noted otherwise. P values represent group differences; ANOVA statistic used with continuous data and chi-square testing for categorical data.
*Two IH participants were diagnosed based on long sleep duration criteria but had normal MSLT results.