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. 2021 Oct 20;8:758668. doi: 10.3389/fmed.2021.758668

Table 1.

Clinical and imaging data in MNV types.

Clinical and Imaging data in MNV Types
Parameter MNV type Number Mean ± STD p Value
1 vs. 2 1 vs. 3 2 vs. 3
Age Type 1 1 77 ± 7 p = 0.158 p = 0.934 p = 0.142
Mixed 2 80 ± 8
Type 2 3 75 ± 7
Speckled fluorescence (quadrants) Type 1 1 1.3 ± 1 p = 0.242 p = 0.745 p = 0.978
Mixed 2 1 ± 1
Type 2 3 1 ± 1
Leakage area (μm2) Type 1 1 4.4 ± 3.5 p = 0.838 p = 0.544 p = 0.768
Mixed 2 3.8 ± 5.4
Type 2 3 4.2 ± 4.1
MNV area Type 1 1 3.5 ± 3.3 p = 0.964 p = 0.225 p = 0.452
Mixed 2 2.6 ± 3.1
Type 2 3 1.5 ± 1.6
MNV/leakage ratio Type 1 1 0.8 ± 0.3 p = 0.03 p = 0.002* p = 0.714
Mixed 2 0.6 ± 0.3
Type 2 3 0.5 ± 0.2
LogMAR BCVA baseline Type 1 1 0.46 ± 0.60 p = 0.845 p = 0.698 p = 0.751
Mixed 2 0.63 ± 0.78
Type 2 3 0.44 ± 0.27
LogMAR BCVA 1-year Type 1 1 0.29 ± 0.28 p = 0.641 p = 0.565 p = 0.742
Mixed 2 0.35 ± 0.27
Type 2 3 0.29 ± 0.34
CMT baseline (μm) Type 1 1 371 ± 77 p = 0.227 p < 0.001* p = 0.005*
Mixed 2 420 ± 91
Type 2 3 503 ± 137
CMT 1-year (μm) Type 1 1 331 ± 73 p = 0.478 p = 0.262 p = 0.411
Mixed 2 368 ± 89
Type 2 3 370 ± 58
N. Intravitreal injections Type 1 1 6 ± 2 p = 0.888 p = 0.956 p = 0.961
Mixed 2 7 ± 2
Type 2 3 7 ± 2
VT MNV Type 1 1 8.5 ± 1.40 p = 0.756 p = 0.842 p = 0.798
Mixed 2 8.5 ± 1.3
Type 2 3 8.1 ± 0.7
VD SCP Type 1 1 0.38 ± 0.02 p = 0.545 p = 0.651 p = 0.498
Mixed 2 0.37 ± 0.02
Type 2 3 0.38 ± 0.02
VD DCP Type 1 1 0.36 ± 0.02 p = 0.631 p = 0.492 p = 0.468
Mixed 2 0.36 ± 0.03
Type 2 3 0.37 ± 0.02
VD CC Type 1 1 0.45 ± 0.03 p = 0.825 p = 0.618 p = 0.522
Mixed 2 0.45 ± 0.03
Type 2 3 0.47 ± 0.02

MNV, macular neovascularization; BCVA, best-corrected visual acuity; CMT, central macular thickness; VT, vessel tortuosity; VD, vessel density; SCP, superficial capillary plexus; DCP, deep capillary plexus; CC, choriocapillaris. Statistically significant values are marked by asterisks (*).