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. 2021 Oct 20;8:758668. doi: 10.3389/fmed.2021.758668

Table 2.

Quantitative analysis in functionally different MNV subgroups (VT cutoff 8.40).

Quantitative analysis in functionally different MNV subgroups (VT cutoff 8.40)
Parameter MNV Subgroups Mean ± STD p
Age Low VT MNV 78 ± 8 0.88
High VT MNV 78 ± 8
Speckled fluorescence (quadrants) Low VT MNV 1.05 ± 1.03 <0.001*
High VT MNV 1.63 ± 0.97
Leakage area (μm2) Low VT MNV 3.78 ± 3.32 0.33
High VT MNV 4.84 ± 5.38
MNV area (μm2) Low VT MNV 2.49 ± 2.91 0.22
High VT MNV 3.55 ± 4.13
MNV/leakage ratio Low VT MNV 0.59 ± 0.31 <0.001*
High VT MNV 0.88 ± 0.24
MNV Type (Type 1/Type 2/Mixed) Low VT MNV 22/10/9 =0.33
High VT MNV 14/8/3
LogMAR BCVA baseline Low VT MNV 0.63 ± 0.71 <0.001*
High VT MNV 0.28 ± 0.25
LogMAR BCVA 1-year Low VT MNV 0.24 ± 0.24 <0.001*
High VT MNV 0.43 ± 0.32
CMT baseline (μm) Low VT MNV 484 ± 88 <0.001*
High VT MNV 380 ± 127
CMT 1-year (μm) Low VT MNV 362 ± 77 0.03
High VT MNV 324 ± 70
N. Intravitreal injections Low VT MNV 7.2 ± 1.5 <0.001*
High VT MNV 5.2 ± 1.9
VT MNV Low VT MNV 7.6 ± 0.4 <0.001*
High VT MNV 9.6 ± 1.4
VD SCP Low VT MNV 0.37 ± 0.02 0.18
High VT MNV 0.38 ± 0.03
VD DCP Low VT MNV 0.37 ± 0.02 <0.001*
High VT MNV 0.34 ± 0.02
VD CC Low VT MNV 0.45 ± 0.03 0.66
High VT MNV 0.45 ± 0.03

MNVs were divided in accordance with a VT cutoff value of 8.40.

MNV, macular neovascularization; BCVA, best-corrected visual acuity; CMT, central macular thickness; VT, vessel tortuosity; VD, vessel density; SCP, superficial capillary plexus; DCP, deep capillary plexus; CC, choriocapillaris.

Statistically significant values are marked by asterisks (*).