Table 1.
Demographics and baseline characteristics stratified by MCE.
| All patients (n = 498) | MCE (n = 97) | Non-MCE (n = 401) | P | |
|---|---|---|---|---|
| Age, mean (SD), y | 66.9 (11.7) | 67 (10.9) | 66.9 (11.8) | 0.995 |
| Male, n (%) | 290 (58.2) | 55 (56.7) | 235 (58.6) | 0.733 |
| No. of BP measurements per patient, mean (SD) | 22 (4.5) | 22 (3.7) | 21 (4.6) | 0.878 |
| Medical history, n (%) | ||||
| Hypertension | 335 (67.3) | 75 (77.3) | 260 (64.8) | 0.019 |
| Diabetes mellitus | 101 (20.3) | 23 (23.7) | 78 (19.5) | 0.349 |
| AF | 236 (47.4) | 47 (48.5) | 189 (47.1) | 0.815 |
| Clinical characteristics, median (IQR) | ||||
| Baseline SBP, mmHg | 145 (128–160) | 150 (132–160) | 143 (128–160) | 0.085 |
| Baseline DBP, mmHg | 80 (72–91) | 83 (70–95) | 80 (74–90) | 0.558 |
| Admission NIHSS scores | 16 (13–20) | 18 (15–21) | 15 (12–19) | <0.001 |
| Admission ASPECT scores | 9 (8–10) | 8 (7–9) | 9 (8–10) | <0.001 |
| TOAST classification, n (%) | 0.113 | |||
| LAA | 169 (33.9) | 27 (27.8) | 142 (35.4) | |
| Cardioembolic | 277 (55.6) | 58 (59.8) | 219 (54.6) | |
| Undetermined or others | 52 (10.5) | 12 (12.4) | 40 (10) | |
| Occlusion location, n (%) | 0.001 | |||
| ICA | 209 (42) | 64 (66) | 145 (36.2) | |
| MCA/ACA (M1/A1) | 254 (51) | 28 (28.9) | 226 (56.4) | |
| MCA/ACA (M2/A2) | 35 (7) | 5 (5.2) | 30 (7.5) | |
| OTP, mean (SD), min | 262.4 (79.8) | 259.5 (76.1) | 263.1 (80.8) | 0.679 |
| OTR, mean (SD), min | 353.3 (93.6) | 377.9 (90.8) | 347.3 (93.4) | <0.001 |
| Collateral score, n (%) | <0.001 | |||
| Grade 0 | 92 (18.5) | 37 (38.1) | 55 (13.7) | |
| Grade 1 | 197 (39.6) | 41 (42.3) | 156 (38.9) | |
| Grade 2 | 209 (42) | 19 (19.6) | 190 (47.4) | |
| Bridging treatment, n (%) | 119 (23.9) | 30 (30.9) | 89 (22.2) | 0.070 |
| Type of procedure, n (%) | 0.194 | |||
| Stent retriever first | 389 (78.2) | 79 (81.4) | 310 (77.3) | |
| Aspiration first | 59 (11.8) | 13 (13.4) | 46 (11.5) | |
| Angioplasty or stent first | 50 (10) | 5 (5.2) | 45 (11.2) | |
| Continuous intravenous antihypertensive agents, n (%) | 306 (61.4) | 61 (62.9) | 245 (61.1) | 0.745 |
| mTICI, 2b/3, n (%) | 364 (73.1) | 51 (52.6) | 313 (78.1) | <0.001 |
| 90-day mRS 0–2, n (%) | 219 (44) | 8 (8.2) | 211 (52.6) | <0.001 |
ASPECT, Alberta Stroke Program Early CT; AF, atrial fibrillation; ACA, anterior cerebral artery; DBP, diastolic blood pressure; ICA, internal carotid artery; LAA, large-artery atherosclerosis; mTICI, modified Thrombolysis in Cerebral Infarction; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; OTP, symptoms onset to groin puncture time; OTR, symptoms onset to reperfusion; SBP, systolic blood pressure.