TABLE 3.

Association of the signature with clinicopathological characteristics in Pituitary adenoma patients.

Variables	Training			Test			Entire
	Low risk	High risk	P	Low risk	High risk	P	Low risk	High risk	P
Sex			1.00			0.36			0.62
Female	8	7		8	11		16	18
Male	9	9		9	5		18	14
Age			0.21			0.12			0.03
≤52	7	11		5	10		12	21
>52	10	5		12	6		22	11
Tumor size classification			0.50			0.40			0.70
Giant	6	3		5	5		11	8
Macro	11	13		12	11		23	24
Invasion			1.00			0.21			0.43
No	6	6		10	5		16	11
Yes	11	10		7	11		18	21

Data were analyzed using the Chi-squared test; p-value < 0.05 was considered to indicate a statistically significant difference.