Table 1.
Variables for modeling exercise.
| Cost () | ||
| • Cost of major bleed | 1,782 | Weighted average (12) |
| • Cost of MI +Ticagrelor | 2,188 | Weighted average (12) |
| • Cost of CMR | 385 | Weighted average (12) |
| • Annual cost of Ticagrelor | 710 | (13) |
| • Annual cost of aspirin | 10 | (13) |
| • Inflation rate | 3% | Assumed |
| Rates | ||
| • Annual rate of major bleed on DAPT | 2.20% | (2, 14) |
| • Annual rate of bleeding on aspirin | 0.60% | Derived (15) |
| • Annual rate of bleeding on no agent | 0.46% | Derived (16) |
| • Mortality rate in first year after diagnosis of unexplained acute myocardial injury and normal coronary angiography | 3.40% | Derived (4) |
| • Mortality rate after first year of diagnosis of unexplained acute myocardial injury and normal coronary angiography | 2.50% | Derived (3) |
| Additional % of repeat MI if not prescribed DAPT and prescribed aspirin only after a diagnosis of unexplained acute myocardial injury and normal coronary angiography | 2.60% | Assumed (16) |
| % of Population with MI requiring DAPT | 25% | Assumed (2, 5) |
DAPT, dual anti platelet therapy; MI, myocardial infarction; CMR, cardiovascular magnetic resonance imaging.