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. 2021 Oct 20;11:742462. doi: 10.3389/fonc.2021.742462

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Copyright © 2021 Huang, Wang, Liu, Chu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Role of TFDP3 in E2F1-induced apoptosis. The diagram summarizes general activation pathways of E2F1-induced apoptosis and the repressive role of TFDP3. The light green part represents p53-dependent mechanisms, and the green part represents p53-independent mechanisms. In the present TFDP3, the effect of E2F1-induced apoptosis is subverted.