Figure 1.

Immunohistochemical labelling in the tibial articular cartilage of mouse knee joints. Immunohistochemical labelling for type X collagen (Col10a1) and matrix metalloproteinase (MMP13) in the 6μm coronal sections of articular cartilage of non-operated and DMM (A), or non-loaded and mechanically loaded (B) middle regions of knee joints of C57BL/6 male mice. White arrows indicate examples of positive labelling, and black arrows indicate a lack of labelling, in the tibiae. Images are representative of results in 4 individual mice. Scale bar = 50μm.