Table 2.

Univariate and multivariate analysis of clinical characteristics.

Variable	Univariate	p value	Multivariate	p value
	HR (95% CI)		HR (95% CI)
Age	1.25 (0.98-1.58)	0.06	–	–
Gender	1.29 (1.04-1.59)	0.02	1.07 (0.86-1.32)	0.53
T stage		<0.001
T1	1	–	1	–
T2	1.55 (1.20-2.00)	<0.001	1.31 (1.00-1.70)	0.047
T3	1.95 (1.38-2.74)	<0.001	1.63 (1.00-2.64)	0.048
T4	2.48 (1.51-4.09)	<0.001	1.79 (0.92-3.50)	0.088
N stage		<0.001
N0	1	–	1	–
N1	1.54 (1.12-1.95)	<0.001	1.40 (0.92-2.11)	0.12
N2	1.91 (1.43-2.56)	<0.001	1.38 (0.69-2.78)	0.36
N3	0.87 (0.21-3.35)	0.85	0.79 (0.17-3.71)	0.77
NX	0.71 (0.23-2.23)	0.56	0.91 (0.29-2.85)	0.87
Tumor stage		<0.001
Stage I	1	–	1	–
Stage II	1.44 (1.14-1.82)	<0.001	0.88 (0.57-1.34)	0.55
Stage III	2.04 (1.58-2.63)	<0.001	1.07 (0.50-2.30)	0.85
Purity	1.89 (0.98-3.63)	0.06	–	–
Risk score	2.40 (2.01-2.85)	<0.001	2.22 (1.85-2.66)	<0.001