Table 2.
Summary of findings for PICO 2. Monitored intensive management of vascular risk factors compared to usual care for the prevention of post-stroke cognitive decline or dementia.
| Certainly assessment | Number of patients | Effect | |||||
|---|---|---|---|---|---|---|---|
| Number of studies | Study design | Intensive management | Usual care | Relative (95% CI) | Absolute (95% CI) | ||
| Dementia | |||||||
| 3 | Randomised trials | 633/12455 (5.1%) | 659/12485 (5.3%) | OR 0.96 (0.86 to 1.07) | 2 fewer per 1.000 (from 7 fewer to 3 more) | ⊕○○○ Very low | Important |
| Cognitive decline (assessed with: various tools) | |||||||
| 5 | Randomised trials | The heterogeneity in interventions and outcomes precluded quantitative meta-analysis. | ⊕○○○ Very low | Important | |||
CI: confidence interval; OR: odds ratio.
Abbreviated for space, full PICO in Supplementary Material.