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. 2021 Nov 3;26(11):116002. doi: 10.1117/1.JBO.26.11.116002

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© 2021 The Authors

Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Fig. 6 — CMV-FLuc BLI of HEKT cells using previous and new devices. (a) Graphs of the light intensity signal are presented either without cells (orange) or with cells (blue). It can be seen that the new device had a higher difference between with and without cells, while the previous device only detected a small signal. (b) Histogram values show the distribution between with and without cell is not so different in the previous device. Quantitatively, the two distributions have a Hellinger distance of 0.08. On the other hand, the new device values show a larger divergence with a Hellinger distance of 0.70. Frame time was 3 s to get highest sensitivity.