Table 1.
Demographics and concurrent medical therapies of patients in the case-control group (N=20) and Dornase alfa treatment group (N=10).
| Demographics | Case-Control (N=20) | Dornase alfa (N=10) | P-Value |
|---|---|---|---|
| Age (years)* | 60 (24-84) | 63 (47-79) | 0.65 |
| Gender** | |||
| Male | 13 (65%) | 6 (60%) | 0.8 |
| Female | 7 (35%) | 4 (40%) | 0.8 |
| Ethnicity** | |||
| White, non-hispanic | 16 (80%) | 8 (80%) | >0.999 |
| African American | 1 (5%) | 0 (0%) | 0.49 |
| Hispanic/Latino | 3 (15%) | 2 (20%) | 0.74 |
| Co-Morbidities** | |||
| Diabetes | 11 (55%) | 7 (70%) | 0.45 |
| Hypertension | 14 (70%) | 9 (90%) | 0.24 |
| Coronary artery | 7 (35%) | 5 (50%) | 0.45 |
| Disease | |||
| Chronic lung disease | 7 (35%) | 3 (30%) | 0.79 |
| (COPD, asthma, ILD) | |||
| Obesity | 17 (85%) | 8 (80%) | 0.79 |
| Therapies Received** | |||
| Remdesivir | 20 (100%) | 9 (90%) | 0.16 |
| Corticosteroids | 20 (100%) | 9 (90%) | 0.16 |
| Antibiotics | 19 (95%) | 10 (100%) | 0.49 |
| Convalescent Plasma | 11 (55%) | 9 (90%) | 0.06 |
| Anticoagulation | 10 (50%) | 4 (40%) | 0.62 |
| Paralytics | 19 (95%) | 8 (80%) | 0.21 |
| Prone positioning | 16 (80%) | 8 (80%) | >0.999 |
*(mean, min to max) **(total and % of patient population). COPD, Chronic Obstructive Pulmonary Disease; ILD, Interstitial Lung Disease.