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. 2021 Oct 20;12:714833. doi: 10.3389/fimmu.2021.714833

Table 1.

Demographics and concurrent medical therapies of patients in the case-control group (N=20) and Dornase alfa treatment group (N=10).

Demographics Case-Control (N=20) Dornase alfa (N=10) P-Value
Age (years)* 60 (24-84) 63 (47-79) 0.65
Gender**
 Male 13 (65%) 6 (60%) 0.8
 Female 7 (35%) 4 (40%) 0.8
Ethnicity**
 White, non-hispanic 16 (80%) 8 (80%) >0.999
 African American 1 (5%) 0 (0%) 0.49
 Hispanic/Latino 3 (15%) 2 (20%) 0.74
Co-Morbidities**
 Diabetes 11 (55%) 7 (70%) 0.45
 Hypertension 14 (70%) 9 (90%) 0.24
 Coronary artery 7 (35%) 5 (50%) 0.45
Disease
 Chronic lung disease 7 (35%) 3 (30%) 0.79
(COPD, asthma, ILD)
 Obesity 17 (85%) 8 (80%) 0.79
Therapies Received**
 Remdesivir 20 (100%) 9 (90%) 0.16
 Corticosteroids 20 (100%) 9 (90%) 0.16
 Antibiotics 19 (95%) 10 (100%) 0.49
 Convalescent Plasma 11 (55%) 9 (90%) 0.06
 Anticoagulation 10 (50%) 4 (40%) 0.62
 Paralytics 19 (95%) 8 (80%) 0.21
 Prone positioning 16 (80%) 8 (80%) >0.999

*(mean, min to max) **(total and % of patient population). COPD, Chronic Obstructive Pulmonary Disease; ILD, Interstitial Lung Disease.