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. 2021 Oct 20;12:733035. doi: 10.3389/fneur.2021.733035

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Copyright © 2021 Öhlmann, Koenen, Labrenz, Engler, Theysohn, Langhorst and Elsenbruch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Regions in which gray matter volume was lower in patients compared to healthy controls are depicted in blue, while regions in which gray matter volume was higher in patients compared to healthy controls are shown in red for patients with (A) ulcerative colitis and (B) irritable bowel syndrome. FWE-correction was applied at the significance level of p < 0.05. Axial slices are provided in Supplementary Figures 1, 3, respectively. For details, see Table 2. AI, anterior insula; IFG, inferior frontal gyrus; IOG, inferior occipital gyrus; ITG, inferior temporal gyrus; LOG, lateral orbital gyrus; MCC, middle cingulate gyrus; MFG, middle frontal gyrus; MTG, middle temporal gyrus; OP, occipital pole; PCG, postcentral gyrus; PCN, precuneus; SFG, superior frontal gyrus; SPL, superior parietal lobule; TP, temporal pole.