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FAK expression alters cytokine production by macrophages infected with Mtb. THP-1, THP-FAKi and THP-FAK+ macrophages were infected with Mtb at an MOI of 10 and cell culture supernatants were collected at 24 hours post-infection. Production of (A) TNF-α (B) IL-1β (C) IL-10 were measured in cell culture supernatants using a human ELISA assay kit. Error bars represent the mean ± SD of three independent biological replicates. *p < 0.05, **p < 0.01, ***p < 0.001.
