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. 2021 Oct 20;12:751594. doi: 10.3389/fimmu.2021.751594

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Copyright © 2021 Liu, Wang, Yuan, Wei and Bai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of immunogenic gene subtypes in the TME of OC. (A) Unsupervised clustering of common DEGs derived from two ICI cluster groups helped divide patients into two subgroups: gene clusters A and B. (B, C) Gene Ontology (GO) enrichment analysis of the gene clusters A and B. (D) OS of all patients was compared between two gene clusters applying Kaplan–Meier curves. (E) Cellular fraction of the tumor-infiltrating immune cell types in gene clusters A and B, including stromal score and immune score. *p < 0.05; **p < 0.01; ***p < 0.001; ns, not significant.