Table 1.
Characteristics of patients with MRSA pneumonia and patients with non-MRSA pneumonia after 1:4 matching
| MRSA pneumonia | Non-MRSA pneumonia | p-value | |||
|---|---|---|---|---|---|
| n (%) | n (%) | ||||
| Sex | 0.943 | ||||
| Male | 2059 | (66.4) | 8186 | (66.4) | |
| Female | 1043 | (33.6) | 4134 | (33.6) | |
| Age (years, mean ± SD) | 79.6 ± 10.7 | 79.5 ± 10.5 | 0.698 | ||
| Body mass index (kg/m2) | < 0.001 | ||||
| < 18.5 | 1388 | (44.7) | 3539 | (28.7) | |
| 18.5–24.9 | 1136 | (36.6) | 5899 | (47.9) | |
| 25–29.9 | 116 | (3.7) | 1147 | (9.3) | |
| ≥ 30 | 28 | (0.9) | 199 | (1.6) | |
| Missing | 434 | (14.0) | 1536 | (12.5) | |
| ADL score (Barthel Index) | < 0.001 | ||||
| 85–100 | 474 | (15.3) | 4144 | (33.4) | |
| 60–80 | 159 | (5.1) | 991 | (8.0) | |
| 0–55 | 2024 | (65.2) | 5503 | (44.7) | |
| Missing | 445 | (14.3) | 1712 | (13.9) | |
| Smoking history | 0.003 | ||||
| Yes | 1226 | (39.5) | 5239 | (42.5) | |
| No | 1876 | (60.5) | 7086 | (57.5) | |
| Hugh-Jones grade | < 0.001 | ||||
| I | 132 | (4.3) | 1604 | (13.0) | |
| II | 193 | (6.2) | 1774 | (14.4) | |
| III | 231 | (7.5) | 1411 | (11.5) | |
| IV | 435 | (14.0) | 2444 | (19.8) | |
| V | 948 | (30.6) | 2375 | (19.3) | |
| Missing | 1163 | (37.5) | 2712 | (22.0) | |
| A-DROP score | < 0.001 | ||||
| 0 | 162 | (5.2) | 1089 | (8.8) | |
| 1 | 639 | (20.6) | 3882 | (31.5) | |
| 2 | 870 | (28.0) | 3871 | (31.4) | |
| 3 | 701 | (22.6) | 2099 | (17.0) | |
| 4 | 410 | (13.2) | 791 | (6.4) | |
| 5 | 218 | (7.0) | 316 | (2.6) | |
| Missing | 102 | (3.3) | 272 | (2.2) | |
| Dehydration | < 0.001 | ||||
| Yes | 1788 | (55.6) | 5443 | (44.2) | |
| No | 1288 | (41.5) | 6779 | (55.0) | |
| Missing | 26 | (0.8) | 98 | (0.8) | |
| Respiratory failure | < 0.001 | ||||
| Yes | 1612 | (52.0) | 4591 | (37.3) | |
| No | 1468 | (47.3) | 7642 | (62.0) | |
| Missing | 22 | (0.7) | 87 | (0.7) | |
| Orientation disturbance | < 0.001 | ||||
| Yes | 941 | (30.3) | 1934 | (15.7) | |
| No | 2100 | (67.7) | 10,285 | (83.5) | |
| Missing | 61 | (2.0) | 101 | (0.8) | |
| Systolic blood pressure | < 0.001 | ||||
| < 90 mmHg | 502 | (16.2) | 1013 | (8.2) | |
| ≥ 90 mmHg | 2581 | (83.2) | 11,243 | (91.3) | |
| Missing | 19 | (0.6) | 64 | (0.5) | |
| CRP ≥ 20 mg/mL or infiltration covering at least two-thirds of one lung on chest radiography | < 0.001 | ||||
| Yes | 477 | (15.4) | 1369 | (11.1) | |
| No | 1030 | (33.2) | 5185 | (42.1) | |
| Missing | 1595 | (51.4) | 5766 | (46.8) | |
| Mechanical ventilation at admission | < 0.001 | ||||
| Yes | 263 | (8.5) | 408 | (3.3) | |
| No | 2839 | (91.5) | 11,912 | (96.7) | |
| ICU admission | < 0.001 | ||||
| Yes | 101 | (3.3) | 157 | (1.3) | |
| No | 3001 | (96.7) | 12,163 | (98.7) | |
| Haemodialysis | < 0.001 | ||||
| Yes | 115 | (3.7) | 216 | (1.8) | |
| No | 2987 | (96.3) | 12,104 | (98.2) | |
| Emergency transport | < 0.001 | ||||
| Yes | 1061 | (34.2) | 3524 | (28.6) | |
| No | 2401 | (65.8) | 8796 | (71.4) | |
| COPD | 0.003 | ||||
| Yes | 328 | (10.6) | 1548 | (12.6) | |
| No | 2774 | (89.4) | 10,772 | (87.4) | |
| Interstitial lung disease | 0.231 | ||||
| Yes | 88 | (2.8) | 404 | (3.3) | |
| No | 3014 | (97.2) | 11,916 | (96.7) | |
| Aspiration pneumonia | < 0.001 | ||||
| Yes | 229 | (7.4) | 206 | (1.7) | |
| No | 2873 | (92.6) | 12,114 | (98.3) | |
| Pseudomonas aeruginosa | 0.635 | ||||
| Pneumonia | |||||
| Yes | 67 | (2.2) | 287 | (2.3) | |
| No | 3035 | (97.8) | 12,033 | (97.7) | |
| Diabetes | 0.999 | ||||
| Yes | 571 | (18.4) | 2268 | (18.4) | |
| No | 2531 | (81.6) | 10,052 | (81.6) | |
MRSA, methicillin-resistant Staphylococcus aureus; ADL, activities of daily living; A-DROP, Age, Dehydration, Respiratory Failure, Orientation Disturbance and Blood Pressure; CRP, C-reactive protein; ICU, intensive care unit; COPD; chronic obstructive pulmonary disease