Table 4.
Risk of mortality among propensity score-matched sample, colistin vs. new agents by AKI status
Final stepwise model—joint effect of AKI and treatment typea | OR estimate | Lower 95% CI | Upper 95% CI | p value |
---|---|---|---|---|
Ventilated at ANY point | 15.87 | 5.69 | 44.23 | < 0.0001 |
Age | 1.03 | 1.01 | 1.06 | 0.0056 |
Rheumatologic disease | 4.81 | 0.67 | 34.78 | 0.1196 |
Mild liver disease | 3.01 | 1.08 | 8.44 | 0.0358 |
Malignancy | 12.95 | 5.16 | 32.49 | < 0.0001 |
New agent AKI vs. new agent no AKI | 1.67 | 0.60 | 4.67 | 0.3312 |
Colistin no AKI vs. new agent no AKI | 0.88 | 0.41 | 1.90 | 0.7415 |
Colistin AKI vs. new agent no AKI | 5.37 | 2.31 | 12.49 | < 0.0001 |
Colistin AKI vs. new agent AKIb | 3.23 | 1.09 | 9.52 | 0.0347 |
Colistin AKI vs. colistin no AKIb | 6.13 | 2.53 | 14.71 | < 0.0001 |
AKI acute kidney injury
aStepwise algorithm eliminating covariates with p value > 0.15 except for treatment and AKI
bNot a model coefficient