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. 2021 Oct 20;12:732874. doi: 10.3389/fphar.2021.732874

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Copyright © 2021 Li, Ke, Guo, Wu, Bian, Shan, Liu, Huo, Guo, Liu, Liu and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) HBMECs was treated with quercetin (0.1, 0.5, 1 μmol/L) and H/R, ROS level was measured using DCFH-DA probe (B) Fluorescence intensity represents ROS expression (C) MDA was detected with ELISA (D) SOD was evaluated using ELISA. ^### p < 0.001 compared to control group; ^* p < 0.05, ^*** p < 0.001 compared to H/R group. μM: μmol/L; ROS: Reactive oxygen species; MDA: Malondialdehyde; SOD: Superoxide dismutase; H/R: Hypoxia and reoxygenation, n = 3.