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. 2021 Oct 20;12:764737. doi: 10.3389/fphys.2021.764737

FIGURE 2.

FIGURE 2

Postprandial glucose and insulin responses to a standardized breakfast meal after 3 weeks of CSR with and without concurrent recurrent circadian disruption (RCD). Glucose and insulin 180-min Area-Under-the-Curves (AUCs) at baseline (BL), after 3 weeks of exposure (EXP), and near the end of recovery (REC) in the CSR group (n = 9; A,C), and the CSR&RCD group (n = 21; B,D). For postprandial glucose and insulin responses in the Control groups, see Zitting and Vetrivelan (submitted). LSmeans and 95% bootstrapping confidence intervals are shown in black, while individual raw data is shown in dotted red lines (low-fat diet) or solid gray lines (high-fat diet). Bonferroni-adjusted bootstrapping p-values are indicated as follows: *p ≤ 0.05 and ***p ≤ 0.001.