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. 2021 Sep 28;11(11):2988–3004. doi: 10.1002/2211-5463.13283

Table 1.

Gene ontology enrichment analysis of top 20 hub genes.

Category Term Count P value
GOTERM_BP_DIRECT GO:1900747˜negative regulation of vascular endothelial growth factor signaling pathway 2 0.007687913
GOTERM_BP_DIRECT GO:0030195˜negative regulation of blood coagulation 2 0.009218762
GOTERM_BP_DIRECT GO:0051894˜positive regulation of focal adhesion assembly 2 0.022896079
GOTERM_BP_DIRECT GO:0030168˜platelet activation 2 0.037883252
GOTERM_BP_DIRECT GO:0043066˜negative regulation of apoptotic process 3 0.039124532
GOTERM_CC_DIRECT GO:0070062˜extracellular exosome 13 2.34E‐06
GOTERM_CC_DIRECT GO:0072562˜blood microparticle 5 2.83E‐06
GOTERM_CC_DIRECT GO:0005578˜proteinaceous extracellular matrix 5 5.98E‐05
GOTERM_CC_DIRECT GO:0005615˜extracellular space 8 6.18E‐05
GOTERM_CC_DIRECT GO:0016324˜apical plasma membrane 3 0.081389039
GOTERM_MF_DIRECT GO:0015377˜cation:chloride symporter activity 2 0.004898581
GOTERM_MF_DIRECT GO:0001968˜fibronectin binding 2 0.008151664
GOTERM_MF_DIRECT GO:0005518˜collagen binding 2 0.011394669
GOTERM_MF_DIRECT GO:0043395˜heparan sulfate proteoglycan binding 2 0.017850569
GOTERM_MF_DIRECT GO:0004869˜cysteine‐type endopeptidase inhibitor activity 2 0.032230616