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. 2021 Oct 20;12:757194. doi: 10.3389/fphar.2021.757194

FIGURE 1.

FIGURE 1

Preparation of orthotopic transplantation liver cancer model with SD. (A) Flow chart; (B) transplantation process: 1) shave and disinfect the surgical area, 2) squeeze out the liver lobe, 3) inoculate the tumor mass, 4) suture the wound; (C) comparison of tumor size; (D) bodyweight change curve; (E) SD score statistics; (F) changes in the diet of mice during the preparation of SD model; (G) stop swimming time statistics. n = 3, *p < 0.05, **p < 0.01, ***p < 0.001.