Figure 6.

RACev preferentially accumulates to the ischemic myocardium. Representative histological findings of infarcted tissue (A) in control groups; (B) MSCev showed less infiltration in the ischemic myocardium, whereas (C) large amount of RACev accumulated into the infarcted tissue, and the labeled some RACev (red color) were internalized into the cardiomyocyte nuclei (yellow arrows; nuclei stained with Hoechst). (D,E) in vivo imaging system (IVIS) imaging showed large accumulation of labeled RACev into the infarcted left anterior ventricle. All experiments were repeated twice with the same results. Statistical significance was determined using the Mann-Whitney U test. The results are presented as mean ± SEM (n = 6 per group).