TABLE 2.

Performance comparison of all models.

Method	AUC [95% CI]	Accuracy	Sensitivity	Specificity	Youden’s index
PRS	0.56 [0.42; 0.81]	0.60	0.62	0.56	0.21
Deep learning	0.67 [0.47; 0.83]	0.60	0.42	0.88	0.29
LASSO w/feature selection	0.85 [0.72; 0.96]	0.81	0.81	0.80	0.61
LASSO w/o feature selection	0.51 [0.39; 0.63]	0.62	0.87	0.09	0.12