TABLE 2.

Risk of bias summary of cross-over studies.

Registered ID of Trials	Risk of bias arising from the randomization process	Risk of bias arising from period and carryover effects	Risk of bias due to deviations from the intended interventions (effect of assignment to intervention)	Risk of bias due to deviations from the intended interventions (effect of adhering to intervention)	Risk of bias due to missing outcome data	Risk of bias in measurement of the outcome	Risk of bias in selection of the reported result	Overall risk of bias
NCT01704404	Low risk	Low risk	Some concerns	Low risk	Low risk	Low risk	Some concerns	Some concerns
NCT02109172	Some concerns	Low risk	Some concerns	Low risk	Low risk	Low risk	Low risk	Some concerns
NCT03064113	Some concerns	Some concerns	Some concerns	Low risk	Low risk	Low risk	Low risk	Some concerns