Figure 4.
Positions of identified signatures in the structural and functional domains of PB2 (A), PB1 (B), PA (C), and PB1-F2 (D) proteins. The positions and dominant amino acid residues of Avian→ Canine (H3N2) signatures are placed below the pale-yellow bar. Black star: Avian→ Canine (H3N2), blue circle: Equine→ Canine (H3N8), brown hexagon: Avian→ Equine (H3N8), red triangle: Avian→ Human (H3N2), green square: Avian→ Swine (H3N2), and purple triangle rhomb: Swine→ Human (H3N2). The detail of these signatures are in Table 2.
