Table 2.
CHD-subtype cohort-prevalences across 4 African studies (10–12) compared with the global birth prevalence meta-analysis by Liu et al. (8).
| Study | Sulafa and Karani (12), | Ekure et al. (11), | PROTEA, | Namuyonga et al. (10), | Liu et al. (8), |
|---|---|---|---|---|---|
| Sudan | Nigeria | South Africa | Uganda | Global | |
| N = 435 | N = 1,296 | N = 1,597 | N = 3,526 | N = 116,1030 | |
| CHD-Subtype | Cohort-prevalence % | ||||
| Ventricular septal defect (Q21.0) | 16 | 25 | 20 | 27 | 36 |
| Patent ductus arteriosus (Q25.0) | 5 | 12 | 11 | 22 | 10 |
| Atrial septal defect (Q21.1) | 6 | 12 | 11 | 9 | 15 |
| Atrioventricular septal defect (Q21.2) | 9 | 6 | 7 | 8 | 4 |
| Pulmonary stenosis (Q22.1) | 6 | 2 | 5 | 6 | 6 |
| Tetralogy of Fallot (Q21.3) | 18 | 12 | 5 | 7 | 4 |
| Coarctation of the aorta (Q25.1) | 0.7 | 0.8 | 3 | 0.4 | 4 |
| Pulmonary atresia (Q22.0) | 3 | 0.4 | 3 | 2.0 | 1 |
| Aortic regurgitation (Q23.1) | Not reported | 0.4 | 3 | 0.2 | 2 |
| Double outlet right ventricle (Q20.2) | 3 | 3 | 3 | 3 | 1 |
| Transposition of the great arteries (Q20.3) | 7 | 2 | 2 | 2 | 4 |
| Tricuspid atresia or stenosis (Q22.4) | 3 | 2 | 1 | 2 | 1 |
| Total anomalous pulmonary venous return (Q26.2) | 1 | 0.5 | 1 | 0.2 | 1 |
| Aortic stenosis (Q23.0) | 1 | Not reported | 1 | 0.9 | 2 |
Results are highlighted in bold and in pink where African cohort-prevalences are lower or in green where they are higher.