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PLIN2KD induces ER stress. Heat maps showing how PLIN2KD influences the expression of genes involved in ER stress (A) and ER Ca2+ homeostasis (D). The color keys represent the row-wise Z score. B: Quantitative real-time PCR analysis of selected ER stress and ER Ca2+ regulators from panels A and D. C: A representative immunoblot of sXBP1 and ACTIN protein levels in Sham, PLIN2KD, and PLIN2OE cells. All error bars indicate SD. n = 3. *P < 0.05, **P < 0.01, ***P < 0.001 vs. Sham.
