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PLIN2KD influences β-cell identity. A: Heat maps illustrating the changes in PLIN2KD cells in expression of key β-cell signature genes, non–β-cell hormone genes, disallowed genes, and genes enriched in embryonic progenitors and dedifferentiated β-cells. The color keys represent the row-wise Z score. B: Quantitative real-time PCR results of candidates in Sham, PLIN2KD, and PLIN2OE cells. All error bars indicate SD. n = 3–4. *P < 0.05, **P < 0.01, ***P < 0.001 vs. Sham.
