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. 2021 Sep 15;70(11):2518–2531. doi: 10.2337/db21-0398

Figure 5.

Figure 5

Molidustat decreases cardiac fatty acid metabolism in T2D. Cardiac fatty acid oxidation rates in control and diabetic rats, with and without molidustat treatment (A). Myocardial triglyceride concentrations, MCAD activity, uncoupling protein 3 (UCP3) protein, and fatty acid translocase (FAT/CD36) protein within the myocardium of control and diabetic rats, with and without molidustat treatment (BE). *P < 0.05 vs. control; #P < 0.05 vs. diabetic untreated; γP < 0.05 significant interaction between disease and drug treatment. a.u, arbitrary units.