Figure 4.

Decision curve analysis (DCA) for each model (clinical model, radiomic model, and integrated Rad+Clin model). The integrated Rad+Clin model had the highest net benefit in predicting which high-risk patients should receive more aggressive treatment, as compared with radiomic model, a clinical model, and simple strategies such as to treat all patients or no patients. This analysis was performed across the full range of threshold probabilities at which a patient would be selected to undergo follow-up imaging.