Table 4.
Identified publicly available gene datasets including immature, tolerogenic and mature DC for tolDC gene set validation.
| Dataset ID | Platform ID | References | Sample Proportions | Agent Used to Induce the tolDC Phenotype |
|---|---|---|---|---|
| GSE104438 | GPL14550 | (26) | 4 x Macrophage, 4 x imDC 4 x tolDC |
Low dose GM-CSF |
| GSE98480 | GPL10558 | (27) | 3 x imDC 3 x imDC + LPS 3 x tolDC 3 x imDC + Poly I:C |
Toll like receptor 7/8 ligand (R848) |
| GSE92852 | GPL18460 | (28) | 3 x imDC 3 x imDC + LPS 3x tolDC 3 x tolDC + LPS |
Interleukin-10 |
| E-MTAB-6937 (ArrayDatabase) | – | (19) | 5 x imDC 5 x imDC + LPS 5 x rapa-tolDC 5 x dexa-tolDC 5 x vitD3-tolDC |
Rapamycin Dexamethasone Vitamin D |