Table 3.
Difference in gray matter volume in each network between the groups.
| Network | Region | Side | BA |
AUD (N = 22) |
HC (N = 22) |
t |
|---|---|---|---|---|---|---|
| ASN | ACC, mPFC, SMA | B | 6, 8, 24, 32 | 10.064 (1.247) |
10.818 (1.003) |
2.18* |
| PSN | Th | L | 0.340 (0.070) |
0.378 (0.053) |
2.03* | |
| LVI | L | 0.029 (0.009) |
0.034 (0.010) |
2.10* | ||
| PI | R | 48 | 0.609 (0.090) |
0.676 (0.056) |
2.95** | |
| DDMN | mPFC, ACC, OFC | B | 9, 10, 11, 24, 32 | 18.880 (2.036) |
19.983 (1.565) |
2.12* |
| Hip | L | 20, 30, 36 | 1.421 (0.091) |
1.516 (0.119) |
2.90** | |
| Hip | R | 20, 30, 36 | 0.479 (0.037) |
0.525 (0.045) |
2.83** | |
| VDMN | PHG | L | 20, 37 | 0.695 (0.076) |
0.768 (0.086) |
2.94** |
| PHG | R | 30, 37 | 0.399 (0.047) |
0.437 (0.047) |
2.63* | |
| LIX | R | 0.296 (0.048) |
0.328 (0.048) |
2.10* | ||
| LECN | MFG, SFG | L | 8, 9 | 1.566 (0.230) |
1.747 (0.283) |
2.28* |
| IFG, OFG | L | 10, 45, 47 | 1.285 (0.174) |
1.434 (0.172) |
2.81** | |
| RECN | CI, CII, LVI | L | 8.849 (0.935) |
9.605 (1.106) |
2.40* |
Values are means (standard deviation) unless indicated otherwise. ACC, anterior cingulate cortex; ASN, anterior salience network; AUD, alcohol use disorder group; CI, Crus I; CII, Crus II; DDMN, dorsal default mode network; HC, healthy control group; Hip, hippocampus; L, left; LIX, lobule IX; LVI, lobule VI; MFG, middle frontal gyrus; mPFC, medial prefrontal cortex; LECN, left executive control network; OFG, orbitofrontal gyrus; PC, precuneus; PHG, parahippocampal gyrus; PI, posterior insula; PSN, posterior salience network; R, right; RECN, right executive control network; SFG, superior frontal gyrus; SMA, supplementary motor area; Th, thalamus; VDMN, ventral default mode network.
p < 0.05 and
p < 0.01 for group comparisons.