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. Author manuscript; available in PMC: 2021 Nov 3.
Published in final edited form as: Radiother Oncol. 2019 Sep 26;142:124–132. doi: 10.1016/j.radonc.2019.09.010

Table 2.

Summary of analysis of target coverage and conformity index

Parameter M-ACT2 A2-ACT2 Pb P-ACT2 Pc A1-ACT2 Pd
CTV1a (prescribed dose 70Gy)
 D98% (Gy) 70.21 (0.47) 70.45 (0.24) 0.386 69.16 (1.16) 0.028* 69.80 (0.89) 0.241
 D2% (Gy) 77.35 (1.85) 75.68 (0.72) 0.009* 76.40 (1.18) 0.139 76.24 (1.28) 0.114
 HI (%) 9.54 (2.51) 7.03 (1.06) 0.007* 9.86 (1.83) 0.721 8.75 (1.27) 0.285
 CI (%) 63.92 (5.63) 72.22 (8.29) 0.005* 68.07 (5.48) 0.028* 68.34 (6.44) 0.037*
CTV2a (prescribed dose 63Gy)
 D98% (Gy) 62.49 (1.07) 63.30 (1.03) 0.022* 60.38 (2.24) # 0.017* 61.49 (1.41) # 0.093
 D2% (Gy) 76.50 (2.21) 75.11 (0.97) 0.028* 75.64 (1.47) 0.203 75.64 (1.66) 0.203
 HI (%) 19.51 (2.48) 16.89 (1.25) 0.010* 21.75 (3.85) 0.169 20.24 (2.50) 0.799
 CI (%) 62.29 (7.54) 72.42 (3.96) 0.009* 66.93 (5.19) 0.007* 67.48 (4.33) 0.022*
CTV3a (prescribed dose 57Gy)
 D98% (Gy) 57.11 (1.18) 57.37 (0.41) 0.575 53.47 (3.34) # 0.013* 55.94 (1.02) 0.007*
 D2% (Gy) 65.20 (2.72) 62.52 (1.54) 0.005* 63.85 (2.46) 0.074 63.41 (1.98) 0.022*
 HI (%) 12.89 (4.04) 8.68 (2.45) 0.005* 17.16 (8.35) 0.110 12.36 (4.09) 0.528
 CI (%) 48.58 (9.28) 59.27 (8.88) 0.007* 53.02 (8.63) 0.022* 55.09 (7.35) 0.019*

Abbreviations: M-ACT2 = MCT plan re-calculated on ACT2 data; A2-ACT2 = ACT2 plan calculated on ACT2 data; P-ACT2 = PCT plan re-calculated on ACT2 data; A1-ACT2 = ACT1 plan re-calculated on ACT2 data; Dx = dose delivered to x% of volume; HI = homogeneity index; CI = conformity index.

a

Shown as mean (standard deviation)

b

Comparison of A2-ACT2 plan with M-ACT2 plan

c

Comparison of P-ACT2 plan with M-ACT2 plan

d

Comparison of A1-ACT2 plan with M-ACT2 plan

#

Target coverage is not satisfied

*

P < 0.05