. Author manuscript; available in PMC: 2021 Nov 3.

Published in final edited form as: Radiother Oncol. 2019 Sep 26;142:124–132. doi: 10.1016/j.radonc.2019.09.010

Table 3.

Summary of analysis of dose to organs at risk

Parameter	M-ACT2	A2-ACT2	P^b	P-ACT2	P^c	A1-ACT2	P^d
Spinal cord, D_2% (Gy)^a	37.97 (5.40)	35. 44(3.72)	0.130	36.79 (5.58)	0.798	35.84 (4.30)	0.201
Brain stem, D_2% (Gy)^a	43.75 (7.78)	45.17 (7.11)	0.385	45.36 (7.80)	0.381	44.17 (8.34)	0.641
Optic chiasm, D_2% (Gy)^a	13.84 (7.78)	24.26 (13.10)	0.007^*	24.56 (14.10)	0.010^*	26.67 (14.05)	0.005^*
Mandible, D_mean (Gy)^a	31.94 (3.58)	32.91 (4.22)	0.074	32.66 (3.28)	0.139	33.21 (3.92)	0.074
Left parotid^e, D_mean (Gy)^a	30.41 (2.82)	31.50 (8.86)	0.758	32.82 (5.81)	0.200	34.03 (5.19)	0.136
Right parotid^e, D_mean (Gy)^a	33.54 (4.44)	32.59 (9.53)	0.681	36.05 (9.04)	0.284	33.86 (6.81)	0.791
Larynx, D_mean (Gy)^a	35.19 (3.62)	41.11 (4.16)	0.007^*	43.70 (4.39)	0.005^*	41.09 (4.15)	0.017^*
Esophagus, D_2% (Gy)^a	48.69 (7.09)	51.05 (4.79)	0.027^*	53.29 (6.90)	0.029^*	52.95 (7.40)	0.040^*

Abbreviations: M-ACT2 = MCT plan re-calculated on ACT2 data; A2-ACT2 = ACT2 plan calculated on ACT2 data; P-ACT2 = PCT plan re-calculated on ACT2 data; A1-ACT2 = ACT1 plan re-calculated on ACT2 data.

Shown as mean (standard deviation)

Comparison of A2-ACT2 plan with M-ACT2 plan

Comparison of P-ACT2 plan with M-ACT2 plan

Comparison of A1-ACT2 plan with M-ACT2 plan

The parotids were evaluated with the volume of total parotids minus the volume of CTVs

P < 0.05