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. 2021 May 15;28(11):3009–3021. doi: 10.1038/s41418-021-00797-w

Fig. 4. Kupffer cells are the primary cell type phagocytizing desialylated platelets in the liver.

Fig. 4

A, B Representative confocal microscopic images. CD41 marks platelets, F4/80 marks Kupffer cells, CD31 labels sinusoidal endothelium, and hepatocytes were detected by autofluorescence. C Pseudocolored TEM micrographs of WT or Clec4f−/− ultrathin sections. Red arrow marks a phagocytized platelet. Blue arrows mark potential interactions between platelets and sinusoidal endothelium.