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. 2021 Nov 2;11:21476. doi: 10.1038/s41598-021-00704-w

Table 2.

1028 ADR reports involving herbal medicines in the TADRRS-HM (1998–2016).

Total numbers of ADR reports
1998–2002 2003–2007 2008–2012 2013–2016 Total
n (%) n (%) n (%) n (%) n (%)
Types of reporters
Medical personnel 59 (85.5) 360 (95) 426 (99.5) 145 (95.4) 990 (96.3)
Doctors 19 (27.5) 121 (31.9) 100 (23.4) 27 (17.8) 267 (26.0)
Pharmacists 40 (58.0) 212 (55.9) 279 (65.2) 90 (59.2) 621 (60.4)
Nursing staff 0 (0) 2 (0.5) 1 (0.2) 0 (0) 3 (0.3)
Others# 0 (0) 25 (6.6) 46 (10.7) 28 (19.3) 99 (10.0)
Researchers 5 (7.3) 11 (2.9) 0 (0) 0 (0) 16 (1.6)
Laypersons* 0 (0) 2 (0.5) 2 (0.5) 5 (3.3) 9 (0.9)
Missing data** 5 (7.3) 6 (1.6) 0 (0) 2 (1.3) 13 (1.3)
Total 69 (100) 379 (100) 428 (100) 152 (100) 1028 (100)
Origins of reports
North District 36 (52.2) 263 (69.4) 145 (33.9) 49 (32.2) 493 (48.0)
Central District 2 (2.9) 9 (2.4) 97 (22.7) 68 (44.8) 176 (17.1)
South District 22 (31.9) 54 (14.3) 45 (10.5) 15 (9.9) 136 (13.2)
Eastern District 9 (13.0) 47 (12.4) 117 (27.3) 12 (7.9) 185 (18.0)
Missing data 0 (0) 6 (1.6) 24 (5.6) 8 (5.3) 38 (3.7)
Total 69 (100) 379 (100) 428 (100) 152 (100) 1028 (100)

TADRRS-HM Taiwan Adverse Drug Reaction Reporting System for Herbal Medicine.

*Patients and caregivers.

**Missing data refer to ADR records that were incompletely filled.

#ADR records were filled by medical personnel, without attribution of the person’s professional status.