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. 2021 May 15;28(11):2991–3008. doi: 10.1038/s41418-021-00796-x

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© The Author(s), under exclusive licence to ADMC Associazione Differenziamento e Morte Cellulare 2021

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Fig. 1 — Full-length DDSPs are inactive in the absence of upstream signals. Domains are theoretically expected to bind to their partner domains without interference.