. 2021 Nov 2;4(11):e2129697. doi: 10.1001/jamanetworkopen.2021.29697

Table 3. Multivariable Regression Models for the Breast MRI TMI Summated Scale Score and the Joint Utility Score of a Testing Sequence of Diagnostic Mammography Followed by Breast MRI.

Variable	Breast MRI TMI summated scale score model^a				Joint utility score model^a
	Complete case estimates (n = 206)^b		Multiple imputation estimates (n = 244)^c^,^d		Complete case estimates (n = 206)^e		Multiple imputation estimates (n = 244)^c^,^f
	Parameter estimate (SE)	P value	Parameter estimate (SE)	P value	Parameter estimate (SE)	P value	Parameter estimate (SE)	P value
Intercept^g	83.58 (1.69)	<.001	84.11 (1.59)	<.001	74.19 (2.36)	<.001	74.18 (2.29)	<.001
Age	0.10 (0.08)	.24	0.05 (0.08)	.56	0.05 (0.12)	.67	0.06 (0.11)	.61
Revised 5-item ASC Cancer Worry subscale	−2.75 (0.94)	.004	−2.28 (0.90)	.01	−6.77 (1.31)	<.001	−6.27 (1.31)	<.001
PROMIS-10
Physical T score	0.10 (0.11)	.37	0.10 (0.11)	.34	0.27 (0.15)	.07	0.32 (0.18)	.08
Mental T score	0.21 (0.13)	.11	0.19 (0.13)	.16	0.17 (0.18)	.34	0.11 (0.22)	.63
Race
Black/African American (vs White)	−4.18 (2.10)	.048	−3.11 (2.06)	.13	−3.50 (2.94)	.23	−1.71 (2.96)	.56
Other (vs White)	−1.22 (2.88)	.67	−1.43 (2.84)	.61	−0.27 (4.02)	.95	−0.61 (4.08)	.88
Ethnicity
Hispanic (vs Non-Hispanic or Unknown)	2.74 (3.93)	.49	0.64 (3.77)	.87	−0.64 (5.49)	.91	−0.59 (5.40)	.91
Insurance status
Medicare or other government insurance vs private insurance	−0.41 (2.03)	.84	0.35 (1.92)	.85	1.19 (2.83)	.67	0.67 (2.76)	.81
Medicaid or uninsured vs private insurance	0.64 (3.76)	.86	1.15 (3.86)	.77	1.25 (5.25)	.81	1.06 (5.53)	.85
Decision autonomy preference
Surgeon-selected (vs patient-selected)	1.92 (2.86)	.50	1.93 (2.78)	.49	−1.15 (3.99)	.77	−1.03 (3.99)	.80
Shared (vs patient-selected)	3.39 (1.83)	.06	2.87 (1.71)	.10	2.30 (2.55)	.37	2.84 (2.46)	.25

Abbreviations: ASC, Assessment of Survivor Concerns; MRI, magnetic resonance imaging; PROMIS-10, Patient-Reported Outcomes Measurement Information System–10; TMI, Testing Morbidities Index.

^{^a}

Parameter estimates for continuous covariates are interpreted as the change in mean response per 1-unit increase. Parameter estimates for categorical covariates are interpreted as the difference in mean response in comparison with the reference level.

^{^b}

R² = 0.15 from the multivariable linear regression model.

^{^c}

Multiple imputation for missing covariate data was performed for the subset of patients with available TMI summated scale scores for both modalities (n = 244) (Figure 1).

^{^d}

R² = 0.11 from the multiply imputed multivariable linear regression model.

^{^e}

R² = 0.20 from the multiply imputed multivariable linear regression model.

^{^f}

R² = 0.17 from the multivariable linear regression model.

^{^g}

Continuous covariates were centered. Thus, the intercept can be interpreted as the mean MRI TMI summated scale score (or joint utility score) for patients who are at the mean age (59.1 years), mean ASC cancer worry level (2.41), mean physical (52.40) and mental (51.76) T scores, and who are at the reference level of the categorical covariates (White, non-Hispanic, private insurance, and patient-selected decision preference).