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. 2021 Nov 3;184(24):5932–5949.e15. doi: 10.1016/j.cell.2021.10.027

Figure 1.

Figure 1

Postmortem bedside surgical procedure for tissue sample harvesting

(A) Immediately after the death of a hospitalized COVID-19 patient or a control patient, the ENT team was contacted by phone, and they harvested samples bedside using an adapted endoscopic endonasal transcribriform approach.

(B) Cohort of 68 COVID-19 patients. Time variables are expressed as median and interquartile range Q1–Q3. All other variables are expressed as percentages.

(C–E) Endoscopic images (left) taken prior to harvesting samples of RM (C) and OM (D), and whole OBs (E). Illustrations indicate the location of the resected tissue (marked in blue) on a coronal section (middle) and a parasagittal (C) or midsagittal (D and E) section (right). Frozen frames were collected from the video of the procedure performed in the right nasal cavity of COVID #33 with a 4 mm 0° endoscope.

IT, inferior turbinate; MT, middle turbinate; NS, nasal septum; OC, olfactory cleft. The 3D head models show the corresponding planes. See also Figure S1, Figure S3, and S4.