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The formation of a molten globule under acidic conditions.A and C, CD spectra of β2m obtained before amyloid formation at varying concentrations of HCl (A) and H2SO4 (C) without ultrasonication. B and D, CD ellipticities at 220 nm at varying concentrations of HCl (B) and H2SO4 (D). The concentration ranges to form monomer, amyloid fibrils, and amorphous aggregates are shown in gray, light blue, and pink, respectively.
