| 14 years prior | The patient underwent mitral valve repair for a P2 prolapse (quadrangular resection and annuloplasty witd a 28-mm flexible band) |
| 12 years prior | Transthoracic echocardiogram (TTE) showed normal left ventricular function with mild systolic anterior motion (SAM) and mild mitral regurgitation (MR) |
| Re-admission | The patient presented with signs of congestive heart failure. TTE revealed normal left ventricular function with significant SAM resulting in left ventricular outflow tract obstruction and severe MR |
| Day 6 | Transoesophageal echocardiogram (TOE) demonstrated significant SAM of the anterior mitral leaflet, resulting in the detachment from the posterior mitral leaflet in mid-to-late systole with severe MR |
| Days 7–15 | Exhaustive medical therapies were tried but intolerant or ineffective; therefore, an invasive treatment was considered necessary |
| Day 16 | Percutaneous mitral valve edge-to-edge repair was successfully performed. TOE confirmed displacement of the leaflets’ coaptation point towards the left ventricular inflow with resolution of SAM and marked reduction of MR |
| Day 24 | The patient was discharged home after an uneventful recovery with good haemodynamic compensation |
| 1 year later | The patient had no cardiovascular symptoms. Follow-up TTE showed no SAM and mild MR |