TABLE 6.
Comparison of covariate-adjusted associations between the GDQS, MDD-W, and AHEI-2010 (scored using FFQ data) compared with selected outcomes among Ethiopian adults
Comparison Metric | GDQS | Comparison Metric | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Outcome | Statistic | Sex | n | n, Cases | Per 1 SD | P-trend | Per 1 SD | P-trend | P-diff | |
MDD-W | BMI <18.5 kg/m2 | OR (95% CI) | M | 965 | 354 | 1.09 (0.95–1.26) | 0.284 | 0.94 (0.81–1.09) | 0.240 | 0.133 |
F | 1596 | 435 | 0.88 (0.78–0.99) | 0.0431 | 0.86 (0.76–0.97) | 0.0191 | 0.518 | |||
Low MUAC | OR (95% CI) | M | 965 | 566 | 1.13 (0.98–1.30) | 0.120 | 0.91 (0.79–1.05) | 0.133 | 0.054 | |
F | 1596 | 741 | 0.84 (0.76–0.93) | 0.0062 | 0.79 (0.71–0.88) | <0.0013 | 0.281 | |||
Anemia | OR (95% CI) | M | 883 | 80 | 0.81 (0.63–1.04) | 0.057 | 0.74 (0.57–0.96) | 0.0121 | 0.205 | |
F | 1485 | 254 | 0.84 (0.73–0.97) | 0.0271 | 0.75 (0.64–0.88) | 0.0022 | 0.283 | |||
Folate deficiency | OR (95% CI) | M | 976 | 569 | 0.79 (0.68–0.91) | 0.0101 | 0.84 (0.72–0.98) | 0.0211 | 0.578 | |
F | 1604 | 510 | 0.76 (0.65–0.89) | <0.0013 | 0.77 (0.66–0.90) | 0.0012 | 0.748 | |||
Low ferritin | OR (95% CI) | M | 869 | 75 | 1.34 (1.05–1.73) | 0.129 | 1.35 (1.04–1.76) | 0.0241 | 0.628 | |
F | 782 | 173 | 0.94 (0.79–1.13) | 0.829 | 1.09 (0.90–1.32) | 0.237 | 0.184 | |||
B12 deficiency | OR (95% CI) | M | 976 | 394 | 0.91 (0.79–1.04) | 0.204 | 0.96 (0.83–1.11) | 0.428 | 0.402 | |
F | 1604 | 355 | 1.08 (0.93–1.25) | 0.408 | 1.12 (0.96–1.31) | 0.100 | 0.334 | |||
ONA, # | EMM (95% CI) | M | 976 | — | 0.41 (0.32–0.50) | <0.0013 | 0.59 (0.51–0.68) | <0.0013 | 0.0351 | |
F | 1604 | — | 0.32 (0.25–0.39) | <0.0013 | 0.57 (0.50–0.64) | <0.0013 | 0.0042 | |||
BMI ≥25 kg/m2 | OR (95% CI) | M | 965 | 67 | 1.00 (0.76–1.32) | 0.651 | 1.11 (0.84–1.46) | 0.469 | 0.439 | |
F | 1596 | 209 | 1.19 (1.02–1.40) | 0.054 | 1.24 (1.06–1.46) | 0.0331 | 0.408 | |||
Hypertension | OR (95% CI) | M | 976 | 287 | 1.27 (1.10–1.46) | 0.0022 | 1.19 (1.02–1.38) | 0.0131 | 0.403 | |
F | 1604 | 484 | 1.08 (0.97–1.21) | 0.317 | 1.12 (0.99–1.25) | 0.0311 | 0.292 | |||
AHEI-2010 | BMI <18.5 kg/m2 | OR (95% CI) | M | 965 | 354 | 1.09 (0.95–1.26) | 0.284 | 1.08 (0.94–1.25) | 0.198 | 0.744 |
F | 1596 | 435 | 0.88 (0.78–0.99) | 0.0431 | 0.93 (0.83–1.04) | 0.100 | 0.727 | |||
Low MUAC | OR (95% CI) | M | 965 | 566 | 1.13 (0.98–1.30) | 0.120 | 1.17 (1.02–1.35) | 0.0092 | 0.528 | |
F | 1596 | 741 | 0.84 (0.76–0.93) | 0.0062 | 0.87 (0.78–0.96) | 0.0291 | 0.481 | |||
Anemia | OR (95% CI) | M | 883 | 80 | 0.81 (0.63–1.04) | 0.057 | 0.93 (0.74–1.18) | 0.707 | 0.264 | |
F | 1485 | 254 | 0.84 (0.73–0.97) | 0.0271 | 0.86 (0.75–0.98) | 0.105 | 0.432 | |||
Folate deficiency | OR (95% CI) | M | 976 | 569 | 0.79 (0.68–0.91) | 0.0101 | 0.74 (0.64–0.86) | <0.0013 | 0.353 | |
F | 1604 | 510 | 0.76 (0.65–0.89) | <0.0013 | 0.89 (0.76–1.03) | 0.107 | 0.229 | |||
Low ferritin | OR (95% CI) | M | 869 | 75 | 1.34 (1.05–1.73) | 0.129 | 1.16 (0.91–1.50) | 0.304 | 0.227 | |
F | 782 | 173 | 0.94 (0.79–1.13) | 0.829 | 0.88 (0.74–1.05) | 0.357 | 0.388 | |||
B12 deficiency | OR (95% CI) | M | 976 | 394 | 0.91 (0.79–1.04) | 0.204 | 1.05 (0.92–1.21) | 0.337 | 0.161 | |
F | 1604 | 355 | 1.08 (0.93–1.25) | 0.408 | 1.12 (0.97–1.29) | 0.199 | 0.400 | |||
ONA, # | EMM (95% CI) | M | 976 | — | 0.41 (0.32–0.50) | <0.0013 | 0.15 (0.06–0.24) | 0.0062 | 0.0161 | |
F | 1604 | — | 0.32 (0.25–0.39) | <0.0013 | 0.02 (−0.04 to 0.09) | 0.618 | 0.0042 | |||
BMI ≥25 kg/m2 | OR (95% CI) | M | 965 | 67 | 1.00 (0.76–1.32) | 0.651 | 0.86 (0.65–1.13) | 0.176 | 0.210 | |
F | 1596 | 209 | 1.19 (1.02–1.40) | 0.054 | 1.07 (0.91–1.27) | 0.427 | 0.593 | |||
Hypertension | OR (95% CI) | M | 976 | 287 | 1.27 (1.10–1.46) | 0.0022 | 1.16 (1.00–1.34) | 0.134 | 0.353 | |
F | 1604 | 484 | 1.08 (0.97–1.21) | 0.317 | 1.07 (0.96–1.20) | 0.267 | 0.651 |
Excluded from this table: outcomes categorized as lower clinical relevance (the binary measure of energy-adjusted overall nutrient inadequacy and continuous anthropometric and biomarker outcomes); refer to Supplemental Table 7 for expanded results. Models are adjusted for age, urban/rural locality, education level, marital status, and occupation. ONA measures are energy-adjusted and continuous, showing the number of adequate nutrients out of 8. Abbreviations: AHEI-2010, Alternative Healthy Eating Index–2010; EMM, estimated marginal mean; GDQS, Global Diet Quality Score; MDD-W, Minimum Dietary Diversity–Women; MUAC, midupper arm circumference; ONA, overall nutrient adequacy.
Statistical significance of linear trends across metric quintiles (P-trend), and Wald tests comparing trends between the GDQS and other metrics (P-diff): P < 0.05.
Statistical significance of linear trends across metric quintiles (P-trend), and Wald tests comparing trends between the GDQS and other metrics (P-diff): P < 0.01.
Statistical significance of linear trends across metric quintiles (P-trend), and Wald tests comparing trends between the GDQS and other metrics (P-diff): P < 0.001.