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. 2021 Sep 23;18(11):4046–4057. doi: 10.1021/acs.molpharmaceut.1c00468

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© 2021 The Authors. Published by American Chemical Society

Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).

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Effects of RB aqueous solution, RB-TF, and b-TF on the SK-MEL28 and HFFF2 cell growth. Cells were cultured with samples for 48 h. (A) The viability of each cell line depending on the formulation and the concentration tested. (B) Analysis of each formulation’s impact at different concentrations, comparing the growth suppression of the two cell lines. The effect of RB aqueous solution (25 μM) on SK-MEL28 vs the effect of RB-TF (25 μM) on SK-MEL28: p value < 0.05 (*). The effect of RB aqueous solution (50 μM) on SK-MEL28 vs the effect of RB-TF (50 μM) on SK-MEL28: p value < 0.05 (•).