Table 1. Chromatographic Conditions for Determining the Concentration of the Model Drugs by HPLC.
| drug
combination |
||
|---|---|---|
| parameter | ATV-RTV | FDN-IPM |
| flow rate (mL/min) | 0.75 | 1 |
| UV wavelength (nm)a | 240 | 250 |
| mobile phase (%v/v)b | 45:55 | 40:60 |
214 nm was used for samples from flux experiments of ATV, RTV, and FDN.
Water/acetonitrile.