. 2021 Oct 21;18(11):4210–4223. doi: 10.1021/acs.molpharmaceut.1c00716

Table 3. Comparison of Proton Chemical Shifts for Free PZQ and in Complex with β-CD; Atoms with the Largest Detected Difference Marked with Red Shading^a.

*Due to the low solubility of PZQ and overlap, the proton chemical shifts for H1, H2, H3, H6, H18, H19, and H20 were extracted from HSQCe spectra; #H17 and H21 when in complex with β-CD exhibit large broadening of peaks in HSQCe, so chemical shifts could not be extracted at all.

Table 3. Comparison of Proton Chemical Shifts for Free PZQ and in Complex with β-CD; Atoms with the Largest Detected Difference Marked with Red Shadinga.

Table 3. Comparison of Proton Chemical Shifts for Free PZQ and in Complex with β-CD; Atoms with the Largest Detected Difference Marked with Red Shading^a.