Figure 4:

Rare extraintestinal manifestations of IBD that should be recognized: A) 50-year-old patient with indeterminate colitis, presenting with a febrile diffuse papulo-pustular and necrotizing skin eruption that healed with significant scarring and appeared 14 days after onset of treatment with azathioprine (1). B) 17-year-old male patients with CD presented with a symmetrical nontender swelling of the lower lip. The swelling had been present for the previous 5 years. The clinical and histological changes were consistent with the diagnosis of orofacial granulomatosis. Further diagnostic tests confirmed the presence of intestinal CD. (2) C) 48 year old female patient with CD and ileocecal resection presenting with “metastatic CD” of the genital skin with histologically visible granuloma. D) 34 year old female CD patient presenting with a nodular form of skin manifestation in the genital area E) Retroauricular atypical pyoderma in a 35 years of female patient with ulcerative colitis. The patient later on developed a colitis associated rectum carcinoma. F) Pulmonary involvement in a 62 year old patient with ulcerative colitis. The pulmonary changes (bronchiectasis and relapsing infection) developed rapidly after colectomy.^{18, 65}