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. 2021 Nov 3;44(2):330–338. doi: 10.1007/s11096-021-01342-y

Table 5.

Binary logistic regression analysis: the correlation between shocka and early-onset thrombocytopenia

Variables Early-onset thrombocytopeniab (platelet count < 100 × 109/Lc) Early-onset thrombocytopenia (the drop decrease of platelet count was ≥ 25%d)
OR 95%CI P OR 95%CI P
Crude 2.952 1.534–5.681 0.001 2.090 1.242–3.516 0.005
Adjustede 2.709 1.359–5.398 0.005 1.900 1.113–3.243 0.019

Bold values show statistical significance of differences

aShock patients require vasoactive medications

bEarly-onset thrombocytopenia: thrombocytopenia occurrence within 6 days of linezolid treatment initiation

cThrombocytopenia with platelet count < 100 × 109/L and a decrease in 25% or more from baseline of the platelet count

dThrombocytopenia due to a platelet count drop decrease of 25% or more from baseline

eAge, hospitalization days, creatinine clearance rate, baseline platelet count were adjusted for in the regression model as the confounding factors