Table 5.
Binary logistic regression analysis: the correlation between shocka and early-onset thrombocytopenia
| Variables | Early-onset thrombocytopeniab (platelet count < 100 × 109/Lc) | Early-onset thrombocytopenia (the drop decrease of platelet count was ≥ 25%d) | ||||
|---|---|---|---|---|---|---|
| OR | 95%CI | P | OR | 95%CI | P | |
| Crude | 2.952 | 1.534–5.681 | 0.001 | 2.090 | 1.242–3.516 | 0.005 |
| Adjustede | 2.709 | 1.359–5.398 | 0.005 | 1.900 | 1.113–3.243 | 0.019 |
Bold values show statistical significance of differences
aShock patients require vasoactive medications
bEarly-onset thrombocytopenia: thrombocytopenia occurrence within 6 days of linezolid treatment initiation
cThrombocytopenia with platelet count < 100 × 109/L and a decrease in 25% or more from baseline of the platelet count
dThrombocytopenia due to a platelet count drop decrease of 25% or more from baseline
eAge, hospitalization days, creatinine clearance rate, baseline platelet count were adjusted for in the regression model as the confounding factors