Table 1.

Study & Intervention Characteristics

Author/ Year	Intervention Name	Intervention Setting	Sample Characteristics	Cancer Type and Stage	Study Focus			Purpose
					Diet	Physical Activity	Weight
Anton et al. 2013	Strong Survivors Nutrition and Exercise Program for Cancer Survivors and Caregivers (SS)	Not reported (NR)	Sample Size 12 participants (NR survivors, NR family members) Sample Size -Mean age: NR -Sex: NR -Race: NR Family members -Relationship type(s): spouses/partners -Age: Range 27–73 -Sex: 50% male, 50% female -Race: NR	Type(s) Uterine, prostate, breast, leukemia, testicular Stage 0-IIIB	X	X		Explore cancer caregivers’ perceptions of participating in a structured exercise and nutrition program with cancer survivors.
Barber 2013	FitSTEPS for Life® (FSFL)	Community-based exercise site	Sample Size 101 participants (62 survivors, 39 caregivers) Survivors -Mean age: 65.2 -Sex: 79% female, 21% male -Race: White=81%, African American=7%, Hispanic/Latino=5%, Asian/other=5% Family members -Relationship type(s): spouses, parents, children, siblings, relative -Mean age: 62.1 -Medical conditions: 17 hypertension, 15 high cholesterol, 9 arthritis, 3 diabetes, 3 heart disease -Sex: 74% female, 26% male -Race: White=83%, African American =11%, Hispanic/Latino=6% (n=36 reporting)	Type(s) Breast, lung, cervical, endometrial, colorectal, liver, gastric, lymphoma, myeloma, leukemia, melanoma, skin, sarcoma, head, neck, kidney, prostate, brain Stage I-IV		X		Examine associations between cancer survivor and caregiver social support, self-efficacy for physical activity, physical activity behavior, and quality of life.
Cadmus-Bertram et al. 2019	NR	Clinic; home; internet application, online, web-based platform; smartphone app; work site; email	25 dyads (25 survivor, 25 support partner dyads) Survivors -Mean age: 54.4 -Sex: 96% female -Race: White=94%, Hispanic=2%, Black=2%, Multiracial=2% Family members -Family relationship type(s): spouses, relative (broad reference)	Breast and colorectal cancer. Stage I-III		X		Test the feasibility of augmenting survivorship care planning with a multi-level physical activity intervention.
Conlon et al. 2015	Bronx Oncology Living Daily (BOLD) Healthy Living (BHL) Program	Church; clinic; community-based	Sample Size 83 participants (66 cancer survivors, 17 cancer co-survivors) Survivors -Mean age: 59.0 -Sex: 93.9% female -Race: African American=45.4%, White=10.6%, Hispanic=31.8%, Other=12.1% Family members -Relationship type(s): NR (study reported co-cancer survivors as family members, friends, anyone who acts as support) -Mean age: 66.4 -Sex: 100% female -Race: African American=94.1%, Hispanic=5.9%	Type(s) Breast, gynecological, lung. Stage NR	X	X		Facilitate behavior change among cancer survivors to reduce diabetes risk and improve health-related quality of life through nutrition education and physical activity.
Demark-Wahnefried et al. 2014	DAMES (Daughters And MothErS Against Breast Cancer)	Home, print materials	Sample Size 68 dyads (68 mother, 68 daughter dyads) Survivors -Mean age: 61.3 -Sex: 100% female -Race: Non-Hispanic White=74%, African American=18%, Hispanic White=7%, Asian=1% Family members -Relationship type(s): mother/daughter -Mean age: 32.9 -Sex: 100% female -Race: NR	Type(s) Breast Stage 0-III	X	X	X	Explore the feasibility of a mother-daughter weight loss intervention and evaluate individual approach vs. team-based approaches to achieving diet and exercise goals and reductions in body mass index (BMI).
James et al. 2015 Supplemental article: Stacey et al. 2016	The Exercise and Nutrition Routine Improving Cancer Health (ENRICH)	Home, group based sessions (community)	Sample Size 133 participants (96 survivors, 24 caregivers, 12 both cancer survivors and caregivers, 1 missing) Survivors -Mean age: control group 58.1 and intervention group 56.2 -Sex: control 74.1% female, intervention 56.2% female -Race: NR Family members -Relationship type(s): spouses, relative/friend -Mean age & sex: NR -Race: NR	Type(s) Breast, prostate, colorectal, melanoma, non-Hodgkins lymphoma, leukemia, ovarian, and thyroid Stage NR	X	X	X	Report findings of a theory-based, group-delivered, face-to-face multiple health behavior change intervention on behavioral outcomes among survivors and caregivers.
Knobf et al. 2018	Healthy Sisters - Intervention for Women of Color Breast Cancer Survivors (WCBCS)	NR	Sample Size 40 participants (30 survivors, 10 partners) Survivors -Mean age: 55.7 -Sex: 100% female -Race: African American=87.5%, White=2.5%, Hispanic=10% Family members -Relationship type(s): siblings -Mean age: 55.7 -Sex: 100% female -Race: African American=80%, White=10%, Hispanic=10%	Type(s) Breast Stage NR	X	X		Examine feasibility and preliminary efficacy of a culturally grounded lifestyle intervention focused on functional ability, quality of life, and health behaviors.
Manne et al. 2019 Supplemental article: Myers-Virtue et al. 2015	General Health and Wellness (GHW)	Clinic	Sample Size 132 couples (132 survivors, 132 spouses) Survivors -Mean age: 60.7 -100% male -Race: White=78%, African American=17%, Hispanic=3%, Asian=0.8%, Other=0.8% Family members -Relationship type(s): spouse/partners -Mean age: 57.1 -Sex: 100% female -Medical conditions: elevated levels of cancer-specific distress -Race: White=76%, African American=16%, Hispanic=5%, Asian=2%, Other=0.8%	Type(s) Prostate Stage I-III	X	X		Explore the degree of correspondence between physical activity and fruit and vegetable consumption among prostate cancer survivors and spouses using baseline data from an RCT, from which the GHW intervention was a comparison study arm.
Pisu et al. 2017	Restoring Health in You (and Your Partner) through Movement (RHYTHM)	Community-based dance studio	Sample Size 31 couples (31 survivors, 31 partners) Survivors -Mean age: 57.9 -Sex: 100% female -Race: White=77.4%, African American=22.6% Family members -Relationship type(s): spouses/partners -Mean age: 60.7% -Sex: 100% male -Race: White=77.4%, African American=22.6%	Type(s) Endometrial, ovarian, breast, colorectal Stage NR		X		Assess feasibility, acceptability and impact of a ballroom dance intervention on improving quality of life and relationship outcomes in cancer survivors and their partners.
Porter et al. 2018	Move2Health	Home-based via video-conference	Sample Size 20 dyads (20 survivors, 20 partners) Survivors -Mean age: 63.0 -Sex: 70% female -Race (intervention): White=44.4%, African American=22.2%, More than 1 race=33.3%. (control): White=100% Family members -Relationship type(s): spouses/partners -Mean age: 62.8 -Sex: 35% female -Race (intervention): White=55.6%, African American =11.1%, More than one race=33.3%. (control): White=81.8%, More than 1 Race=18.2%	Type(s) Breast and prostate Stage I-IV		X		Determine the acceptability of a couple-based PA intervention delivered via videoconference and the feasibility of conducting a randomized controlled trial testing the intervention among breast and prostate cancer survivors and their partners.
Ross Zahavich et al. 2012	Yoga Thrive	Class-based (location not specified)	Sample Size 25 participants (15 survivors, 10 support persons: 9 spouse, 1 friend) Survivors -Mean age: 64.5 -Sex: 100% male -Race: NR Family members -Relationship type(s): spouse/friend -Mean age: 60.6 -Sex: 100% female -Race: NR	Type(s) Prostate Stage NR		X		Examine the feasibility and benefit of a therapeutic yoga program offered to prostate cancer survivors and their support persons.
St. George et al. 2019	NR	Mobile device use (digital health intervention)	Sample Size 46 participants (a subset of 21 participants completed individual interviews) Survivors -Mean age: 66.1 -Sex: 100% female -Race: Hispanic=34%, non-Hispanic black=33%, non-Hispanic white=33% Family members -Relationship type(s): parent/adult child, grandparent/grandchild -Mean age (adult children): 39.9; (grandchildren): 12.7 -Sex: NR -Race (adult children): Mean Hispanic=2.2, Mean non-Hispanic Black=2.5, Mean non-Hispanic White=2.2. (grandchildren): Mean Hispanic=3.6, Mean non-Hispanic Black=5.6; Mean non-Hispanic White=2.3	Type(s) Breast, endometrial, or ovarian Stage I-III	X	X	X	Design a multigenerational digital lifestyle intervention to improve physical activity, diet and weight among racially and ethnically diverse overweight and obese women cancer survivors by encouraging positive healthy behaviors in their family members (children and grandchildren).
Stoutenberg et al. 2015	Integrated Wellness Program	Clinic	Sample Size 20 participants (16 survivors, 4 caregivers) Survivors -Mean age: 62.5 -Sex: 75% female, 25% male -Race: White=75%, African American=10%, Hispanic=15% Family members -Relationship type(s): NR -Mean age: data combined with survivors -Sex: NR -Race: NR	Type(s) Breast, prostate, gastric, multiple myeloma, pancreatic, and more than one cancer type ( i.e., multiple cancer) Stage NR	X	X		Assess the effectiveness of the Integrative Wellness Program on improving physical activity, nutrition, sleep hygiene, and quality of life program completers.
Winters-Stone et al. 2016	The Exercise Together Project	Oregon Health & Science University (OHSU)	Sample Size 64 couples (64 survivors, 64 spouses) Survivors -Mean age: Intervention (70.6), control (72.9) -Sex: 100% male -Race: Intervention 91%=Caucasian, 97%=Non-Hispanic, Control 94%=Caucasian, 94%=Non-Hispanic Family members -Family relationship type(s): spouses -Mean age: Intervention (66.5), control (69.7) -Sex: 100% female -Race: Intervention 91%=Caucasian, 97%=Non-Hispanic, Control 94%=Caucasian, 94%=Non-Hispanic	Type(s) Prostate Stage NR		X	X	Determine the feasibility and preliminary efficacy of a couples-based approach to exercise training for couples coping with prostate cancer.

Author/Year	Intervention Name	Study Design	Intervention Duration & Follow-Up Period	Brief Description of Intervention Content
Anton et al. 2013	Strong Survivors Nutrition and Exercise Program for Cancer Survivors and Caregivers (SS)	Pre-experimental	Duration 12 weeks Follow-Up 6 months	Basic nutrition and exercise to benefit the physical and psychosocial health of cancer survivors and cancer caregivers.
Barber 2013	FitSTEPS for Life® (FSFL)	Quasi-experimental	Duration NR Follow-Up 1 month	Individually tailored and supervised community-based exercise program for cancer survivors and caregivers.
Cadmus-Bertram et al. 2019	NR	Randomized controlled pilot trial	Duration 12 weeks Follow-Up NR	The control group received a care plan, printed copy of national dietary guidelines, and standardized emails during an 8-week period. The intervention group received a care plan, 12-week physical activity module and Fitbit trackers.
Conlon et al. 2015	Bronx Oncology Living Daily (BOLD) Healthy Living (BHL) Program	Pre-experimental; pilot program	Duration 1 year Follow-Up NR	Weekly group nutrition education and exercise classes (60 to 75 minutes) for 4 weeks or 12 weeks. At-home class materials and physical activities provides to people who missed group sessions.
Demark-Wahnefried et al. 2014	DAMES (Daughters And MothErS Against Breast Cancer)	Three-arm randomized controlled trial	Duration 1 year Follow-Up 6, 12 months	Arm 1: tailored diet and exercise intervention delivered to individuals in dyads Arm 2: tailored diet and exercise intervention emphasizing a team-based approach among dyads Arm 3: Standardized diet and exercise materials All arms received a personalized workbook, informational mailings on a bimonthly basis over the course of a year on exercise and diet (e.g., portion control, nutritious diets, aerobic activity, strength training).
James et al. 2015 Supplemental article: Stacey et al. 2016	The Exercise and Nutrition Routine Improving Cancer Health (ENRICH)	Randomized controlled trial	Duration 8 weeks Follow-Up 20 weeks, 12 months	Information and activities focused on healthy eating, maintaining a healthy weight, a home-based walking program and resources, and a home based resistance training program with information and resources using a mix of didactic information delivery and practical activities.
Knobf et al. 2018	Healthy Sisters - Intervention for Women of Color Breast Cancer Survivors (WCBCS)	Feasibility study	Duration 6 weeks Follow-Up 3, 6 months	Symptom identification and management; physical activity benefits, recommendations, and safety; nutrition choices and strategies; group empowerment and peer support, community resources; health goals; prayer at all sessions.
Manne et al. 2019 Supplemental article: Myers-Virtue et al. 2015	General Health and Wellness (GHW)	Randomized controlled trial	Duration 5 weeks Follow-Up 3, 6 months	Audio-recorded couples’ sessions and a booster call focused on healthy lifestyles, including: dietary assessment, setting goals, adopting a plant-based diet, relaxation, and increasing regular activity.
Pisu et al. 2017	Restoring Health in You (and Your Partner) through Movement (RHYTHM)	Randomized controlled trial with waitlist control	Duration 12 weeks (avg - 14.7 weeks; max - 19 weeks) Follow-Up NR	Couples were taught dances (e.g., Foxtrot, Waltz, Cha-Cha and East Coast Swing) and were expected to practice 5 times per week to increase their physical activity.
Porter et al. 2018	Move2Health	Randomized controlled trial with waitlist control	Duration 2 months Follow-Up 2 months	Videoconference sessions that included training in communication skills to help couples identify and use effective social support strategies, engage in joint decision making about goals and plans for increasing physical activity, and work through barriers to behavior change.
Ross Zahavich et al. 2012	Yoga Thrive	Feasibility study including an adherence and maintenance phase	Duration 14 weeks Follow-Up 7, 14 weeks	Class-based therapeutic yoga program offered to all prostate cancer survivor participants and their support persons and a maintenance phase involving self-selected physical activity.
St. George et al. 2019	NR	Pre-experimental design using the Integrate, Design, Assess, and Share (IDEAS) framework to guide intervention development.	Duration 12 months Follow-Up NR	Didactic content for improving diet and physical activity behaviors (e.g., recipes, exercises), setting and monitoring goals, and enhancing communication. Integrated behavior change and intrinsic motivation-related elements from social cognitive theory (e.g., goal setting, self-regulation, autonomy) and characteristics of positive family relationships from family systems theory (e.g., communication).
Stoutenberg et al. 2015	Integrated Wellness Program	Pre-experimental; pilot program	Duration 1 year Follow-Up NR	Knowledge about the benefits of different health practices such as resistance and cardiovascular exercises, eating habits, and mindfulness technique and applied experiences (i.e., practicing exercises).
Winters-Stone et al. 2016	The Exercise Together Project	Randomized controlled trial	Duration 6 months Follow-Up 3, 6 months	Couples attend group strength-training exercise sessions led by an exercise physiologist with spouse/partners as training partners.