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. 2021 Jul 1;8(8):1248–1252. doi: 10.1002/mdc3.13267

TABLE 1.

Description of clinical features of functional tics within this series

Case Age of onset Sex Phenomenology of tics Vocalizations Suppressibility Presence of premonitory urge Presence of “tic attacks” Unusual triggers Other concurrent somatic manifestations Pharmacological treatment and outcome*
1 16 yr F Dystonic (face); clonic (face, extremities); stereotypic (hands); complex motor with concomitant vocalization Palilalia, short phrases, vowel sounds, sniffing, single words No No Yes Talking to other people Dissociative symptoms of feeling like body parts were not her own, dyspnea, stuttering, transient confusion Guanfacine 0.5 mg at bedtime; all symptoms resolved after 4 doses, discontinued without recurrence of symptoms
2 14 yr F Dystonic (face, neck); clonic (extremities); stereotypic (hands); complex motor with concomitant vocalization Whistling, coprolalia, short phrases, clicking, purring No No Yes Flashing lights, hearing whistling Functional tremor N/A
3 13 yr F Dystonic (face); clonic (face, neck, extremities); stereotypic (hands); complex motor with concomitant vocalization Short phrases, clicking, single words, squeaking Yes** Yes Yes Flashing lights, loud noises, the word “sound”, dampness of her hair, 7 pm every night None

Fluphenazine 0.5 mg every morning and 1 mg at bedtime, led to daytime somnolence, felt as though movements were easier to suppress.

Diazepam 2 mg as needed, allowed for movements to be suppressed, discontinued

4 14 yr F Dystonic (neck); clonic (extremities); stereotypic (hands) Single words, blowing raspberries, squeaking No Yes Yes Presence of other people Functional stereotypy, functional tremor Pimozide 2 mg daily; no improvement, led to daytime somnolence, discontinued
5 14 yr F Dystonic (extremities) Clonic (face, extremities) Stereotypic (hands) Short phrases, coprolalia, whistling No No Yes None Functional tremor N/A
6 14 yr F Dystonic (face, neck, extremities); clonic (face, neck, extremities); stereotypic (hands); complex motor with concomitant vocalization Grunting, vowel sounds, clicking, short phrases, whistling No No Yes Loud noises, loud footsteps, hearing whistling sounds, extremes of temperature None Clonidine 0.1 mg twice daily; no improvement led to daytime somnolence, discontinued

Abbreviations: F, Female.

*

Pharmacological treatments were administered by providers before our evaluation.

**

Movements and sounds were suppressible following initiation of pharmacologic treatment.