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. 2021 Oct 22;6(20):e151527. doi: 10.1172/jci.insight.151527

Figure 4. Measurement of thrombotic and endothelial markers in patients with COVID-19 by disease severity.

Figure 4

Markers included (A) D-dimer, (B) tissue factor, (C) vWF, (D) P selectin, (E) Angpt-2, (F) Angpt-1, (G) Tie2, (H) VEGFR-1, (I) E selectin, (J) thrombomodulin, (K) TFPI, and (L) EPCR. Each data point represents individual patient plasma measurements corresponding to disease severity. Bar indicates median value. Significance among groups determined by Kruskal-Wallis with Dunn’s multiple comparison test, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. S, severe (ICU patients); Mod, moderate (hospitalized, non-ICU); Mild (COVID-19–positive outpatients); and HC, healthy controls.